Aktivitas Antibakteri Ekstrak Etanol Daun Muda dan Daun Tua Tanaman Pepaya (Carica papaya L.) terhadap Bakteri Escherichia coli

Abstract

Escherichia coli is a bacteria that causes diarrhea. One plant that can be used as a treatment for diarrhea is papaya leaves. Papaya leaves contain active compounds such as tannins, alkaloids, flavonoids and saponins which are thought to have antimicrobial effects. Test the antibacterial activity of extracts of young papaya leaves and old papaya leaves using 70% ethanol filter and then evaporate them. The results of evaporating the ethanol extract of young leaves and old leaves will produce a thick extract. The results of the thick extract were then carried out with a phytochemical test to determine the compounds contained in the ethanol extract of papaya leaves, after the phytochemical test then tested against Escherichia coli bacteria. This study aims to analyze the effectiveness of administering ethanol extract of young leaves and old leaves of papaya (Carica papaya L.) plants with various concentrations on antibacterial and growth of Escherichia coli bacteria. This research used a true experimental design with the paper disc diffusion method (Kirby-Bauer). The inhibition zone formed was measured using a ruler and analyzed using the One Way ANOVA test. The research results show that papaya leaf extract can inhibit the growth of Escherichia coli bacteria.