Cost Effectiveness Analysis Penggunaan Ceftriaxone dan Cefotaxime Pasien Gastroenteritis Akut di RSUD Ajibarang Tahun 2023

Abstract

Due to the large number of acute gastroenteritis cases, studies are needed in selecting effective antibiotic therapy. In this study, a pharmacoeconomic approach was used to compare the effectiveness of therapy results and costs of the antibiotics Ceftiaxone and Cefotaxime used in the treatment of acute gastroenteritis. The goals of this research was to determine the effectiveness of two antibiotics, the ACER and ICER values, and to identify the most cost-effective antibioticIn this research, researchers used quantitative methods with descriptive design and retrospective data collection. The data were taken from the medical records of acute gastroenteritis inpatients at Ajibarang Hospital. The population in this study was 198 with inclusion considerations so that a sample of 30 was obtained. The parameters used were length of hospital stay and total direct medical costs including treatment and room costs, laboratory costs, and medication costs. This pharmacoeconomic approach is expressed with ACER (Average Cost-Effectiveness Ratio), which is the value obtained from the average direct medical costs divided by clinical outcomes (% effectiveness of therapy). it can be concluded that ceftriaxone is more cost-effective than cefotaxime with an effectiveness percentage of 87% and 73% respectively, ACER value Rp. 2,662,068 and Rp. 3,394,520. Therefore, ceftriaxone is more cost-effective than cefotaxime. And it is known that the ICER value is IDR. -1,157,143.